Application of staining technology on anterior capsule of lens in white cataract

Abstract

Objective To evaluate the clinical effect by using a quick and direct staining technology in anterior lens capsule in white cataract. Methods In this randomized prospective study, phacoemulsification was performed in 67 eyes of 52 cases with white cataract. The eyes were divided into two groups randomly: Group A and Group B. The anterior capsule of the lens was stained with 0.06% trypan blue before creating continous curvilinear capsulorhexis (CCC) in Group A in 34 eyes, and 0.06% trypan blue with sterilized air was used in Group B in 33 eyes. The following parameters were compared between the two groups, including the success rate of CCC, endothelial cell density, ultrasound energy, effective phacoemulsification time and surgical complications. Results After staining, the anterior capsule presented light blue colour and was easy to be distinguished. In the 67 eyes with white cataract, success rate of CCC was 100%. There was no significant difference in the density of corneal endothelia cell, average ultrasound energy, effective phacoemulsification time or surgical complication between two groups after surgery (P>0.05). There was a lower loss rate of corneal endothelial cell density in Group A (7%±1.1%) than that of Group B (10%±1.2%). The percentage of hexagonal cells in Group A (48.6%±13.5%) was higher than that of Group B (44.0%±9.5%). There was no statistically significant difference between two groups in loss rate of corneal endothelial cell (t=-0.691, P=0.492) and percentage of hexagonal cell (t=-1.509, P=0.137). Conclusion Injection of 0.06% trypan blue into the anterior chamber to stain the anterior lens capsule is safe and effective in white cataract. Key words: Cataract, white; Continuous curvilinear capsulorhexis; Staining, anterior capsule, lens; Trypan-blue