Abstract
Abstract The reaction of dimethyl squarate with aminodeoxy sugars, aminodeoxy alditols, amino aldonic acids, and glycosyl amines under neutral conditions furnished the squaric amide esters, which were converted in more alkaline media (pH ≈8) into the asymmetric squaric diamides. The unprotected squaric acid amide esters are suitable for constructing a specific anchor (spacer, linker) function that favorably influences the water-solubility of the resulting drugs and glycoconjugates.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
