Abstract

Bioactive glasses in the system SiO2-Na2O-CaO-P2O5 were prepared by the conventional melting process at a high temperature in an electric furnace. The densities of the glasses as well as their glass transition temperatures were measured experimentally. Also, the glasses were characterized by solution calorimetry at 298 K in an acidic solvent consisting of HF (6 M) and HNO3 (4 M). A simulation of the bioactivity properties of these obtained glasses was carried out by thermodynamic calculations, with the purpose of understanding the in vitro results obtained.

Highlights

  • In recent decades, the applications of bioactive glasses as bioimplants to repair damaged or diseased bones have escalated, in the context of their ability to form a strong interfacial bond with living tissues

  • Bioactive glasses in the system SiO2-Na2O-CaO-P2O5 were prepared by the conventional melting process at a high temperature in an electric furnace

  • The glasses were characterized by solution calorimetry at 298 K in an acidic solvent consisting of HF (6 M) and HNO3 (4 M)

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Summary

Introduction

The applications of bioactive glasses as bioimplants to repair damaged or diseased bones have escalated, in the context of their ability to form a strong interfacial bond with living tissues. These glasses have been used in many clinical operations during the last twenty years including surgery of human body parts such as ears, teeth, knees and hips. The choice of bioactive glasses for implant applications requires design optimized compositions [1]. Some compositions of glasses in the system SiO2-Na2O-CaO-P2O5, used as biomaterials, are able to form a bond with bone once they are implanted, such as the Bioglass [4,5]. The main advantages of these synthetic biomaterials are availability, reproducibility and reliability [6]

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