Abstract

The efficacy of serum C-reactive protein (CRP) in the diagnosis of subacute thyroiditis (SAT) was investigated.Serum CRP levels were determined at initial presentation of 33 subjects with SAT and 37 patients with Graves' disease.Erythrocyte sedimentation rate (ESR) was measured in all patients by Westergrens' method.The ESR and CRP levels were significantly higher in cases with SAT than in Graves' disease (P<0.01).The best diagnostic cut-off point of CRP was 7.14 mg/L,and serum CRP level was correlated well with that of ESR (r =0.630,P<0.01).This study highlights the scope of using serum CRP as a diagnostic marker of SAT,especially in situations when it seems to be confused with Graves' disease,a common cause of thyrotoxicosis. Key words: C-reactive protein; Graves' disease ; Subacute thyroiditis

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