Abstract
Objective To explore the gender differences of risk stratification of pulmonary thromboembolism (PTE) in non-high-risk PTE patients aged 80 and older and the predictive value of various scores for the severity of PTE in this population. Methods The clinical data of PTE patients aged 80 and older hospitalized in Beijing Tong Ren Hospital, Capital Medical University from January 2011 to June 2018 were retrospectively selected. Risk stratification was perofrmed according to comprehensive risk stratification assessment. PESI, sPESI, new version of sPESI, PERS, Bova score and PREP score were calculated and risk stratified. The gender differences of different scores in elderly patients with PTE were compared and the ability of different scores to judge the severity of elderly patients with PTE was evaluated. Results A total of 118 patients were enrolled, including 72 females (61.0%) with an average age of (83.14±2.89) years, 46 males (39.0%) with an average age of (84.07±3.17) years. There was no significant difference in baseline clinical data between the two groups (P>0.05). The PESI scores of elderly PTE patients had significant gender differences (P<0.05). The PESI stratification was consistent with the sPESI stratification. There were significant gender differences in PESI stratification in low-risk and intermediate-risk groups (P<0.05), no gender differences in other risk stratifications. The Area Under Curve (AUC) of PREP score was 0.828 (95% CI: 0.742-0.914, P<0.05) and Youden index was 0.657 in the low-risk group and the middle-risk group, respectively. Conclusions There were no gender differences in all kinds of risk stratification scores in elderly patients with PTE. PREP score is better than other risk stratification scores and prognosis scores in predicting the severity of PTE in the elderly low-risk group and the intermediate-risk group. Key words: Pulmonary embolism; Risk stratification score; Prognosis score; Advanced age
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