Abstract
Animal experiments were conducted to observe and analyze the therapeutic effect of platelet-rich plasma in regenerated pulp treatment of young permanent teeth, in order to provide valuable guidance on the clinical treatment. Six beagle dogs were selected as study subjects with 54 teeth and 108 root canals. Thirty six teeth were selected as the control group, without any treatment. Another 72 teeth were randomized into the whole blood group (36 teeth) and platelet-rich plasma group (36 teeth) with 72 root canals. The model of periapical periodontitis was established and the X- ray and histological results of the whole blood group and platelet rich plasma group were analyzed using the Fisher exact probability method. After 12 weeks of regenerated endodontic pulp treatment, X-ray examination showed that there was no significant difference between the whole blood group and platelet rich plasma group in terms of periapical shadow reduction, apical hole closure and thickening of root canal wall. Histology results showed that the apical pore part of the root canal in the whole blood group and platelet-rich plasma group was closed and the root canal wall was thickened, the cemenoid tissue deposition occurred in the root canal wall and apical hole and free cemenoid tissue and dental pulp tissue were generated in the root canal. There was no statistical significance between the whole blood group and platelet-rich plasma group in comparison to apical closure, new tissue formation of the root canal wall and endodontic pulp tissue formation. The application of platelet-rich plasma in the treatment of regenerative pulp can make the root of young permanent teeth develop well. If the root periapical tissue fails to bleed to form blood clot in the treatment of regenerative pulp, the stent scheme of platelet-rich plasma is more ideal.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.