Application of Omics Techniques in Skin Homeostasis Evaluation

Abstract

In recent years, skin homeostasis has been paid more attention by cosmetics industry. Many factors can damage skin homeostasis and affect skin health and beauty. Therefore, maintaining skin homeostasis is the basis of cosmetic efficacy, but there is a lack of corresponding evaluation methods. At present, some efficacy claims related to skin homeostasis, such as moisturizing and repairing, are only evaluated from a certain aspect of the skin, which is not completely consistent with the overall concept of homeostasis. With the development of omics technologies especially cutaneous lipidomics, cutaneous microbiome and proteomics technologies, which are based on the systematic concept to systematically analyze the lipidomics, microbiome and proteome that affect the skin. Based on a variety of omics research techniques, combined with steady-state correlation target analysis, more comprehensive and in-depth analysis can be conducted, which is a potential emerging evaluation method for skin homeostasis maintenance. In this paper, the future development direction of the evaluation method of homeostasis maintenance is forecasted, which provides a theoretical basis for the development of cosmetics for maintaining skin homeostasis.