Abstract

67 Background: This study determined whether online continuing medical education could improve the knowledge and confidence of cliniciansin the application of the latest strategies for the treatment of mCRC. Methods: A 30-minute online video panel discussion was launched for physicians outside the USA in March 2020. Data was collected to May 2020. Educational effect assessed with repeated-pairs pre-/post-activity, where individual participants served as their own control. 3 multiple-choice, knowledge questions and 1 self-efficacy, 5-point Likert scale confidence question were analyzed. Chi-squared test assessed pre- to post-activity change (5% significance level, P < .05). Magnitude of change in total number of correct responses overall, and for each question, were determined with Cramer’s V ( < .06 = Modest, 0.06-0.15 = Noticeable, .16-.26 = Considerable, > .26 = Extensive). Results: 108 oncologists (oncs) and 33 gastroenterologists (gastros) completed pre- and post-activity questions. A positive educational effect was observed for oncs (noticeable effect, V = .123, P < .01); average % correct increased from 71 to 81%. For gastros, there was a noticeable effect (V = .06) but P was not significant; correct responses increased from 49 to 56%. Clinicians with 3/3 answers correct increased post-activity (37 to 54% for oncs, 18 to 24%, for gastros). For oncs, improvements in % of correct responses post-activity were seen for questions on tailoring treatment to primary tumour location, outcome of the CRICKET trial on cetuximab re-challenge, and outcome of the BEACON trial in BRAF mutated mCRC (11%, 21%, and 13% relative changes, respectively). Relative changes of 25%, 18% and -17%, respectively, were observed for gastros. % of clinicians mostly or very confident with selecting optimal treatment strategy across the continuum of care improved post-activity, increasing from 33 to 58% for oncs and from 27 to 36% for gastros. Conclusions: This on-demand, online video panel discussion resulted in a positive education effect. However, the sample size for gastros was small and the post-activity change was not significant. Knowledge gaps remained post-activity, indicating the need for further education to support optimisation of the treatment of mCRC.

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