Application of Narcotrend-Assisted Anesthesia In-Depth Monitor During Total Intravenous Anesthesia in Children

Abstract

Objective To explore the application of Narcotrend-assisted anesthesia in-depth monitor during total intravenous anesthesia in children. Methods From June to November 2013,a total of 40 children who underwent abdominal surgery were included in the study randomly. They were divided into Narcotrend group (n = 20) and control group (n = 20). All patients received total intravenous anesthesia with propofol and remifentanil. The patients in Narcotrend group adjusted anesthesia in-depth according to Narcotrend index (NTI). Those patients in control group adjusted anesthesia in-depth according to their heart rate(HR), mean arterial pressure (MAP) and movement. Changes of hemodynamics, durations of emergence and tracheal extubation were recorded. The doses of propofol and remifentanil and the incidence rates of postoperative nasea and vomiting were also recorded. The study protocol was approved by the Ethical Review Board of Investigation in Human Being of Guangzhou Women and Children's Medical Center. Informed consent was obtained from each participants' parents. Results There were no significant differences in HR and MAP at 5 observation time points between two groups (P> 0.05). The dose of propofol was lower in Narcotrend group than that of control group [(122.71±21.06) mg vs. (181.08±25.97) mg, P< 0.01]. The durations of emergence and tracheal extubation were respectively shorter in Narcotrend group than those of control group [(4.37±2.05) min vs. (9.15±5.13) min, (6.68±2.32) min vs. (12.45±5.15) min; P<0.01]. No one had postoperative nausea and vomiting in both groups. Conclusion Narcotrend-assisted anesthesia in-depth monitor can contribute to reduce the dose of propofol and shorten the duration of recovery during total intravenous anesthesia with propofol and remifentanil. Key words: Narcotrend; Monitoring, intraoperative; Anesthesia, general; Child