Abstract
Traditional dressings used for wound repair, such as gauze, have shortcomings; for example, they cannot provide a suitable microenvironment for wound recovery. Therefore, it is necessary to find a better dressing to overcome shortcomings. Hydrogel provides a suitable wet environment, has good biocompatibility, and has a strong swelling rate to absorb exudate. Nanomaterial in hydrogels has been used to improve their performance and overcome the shortcomings of current hydrogel dressings. Hydrogel dressing can also be loaded with nanodrug particles to exert a better therapeutic effect than conventional drugs and to make the dressing more practical. This article reviews the application of nanotechnology in hydrogels related to wound healing and discusses the application prospects of nanohydrogels. After searching for hydrogel articles related to wound healing, we found that nanomaterial can not only enhance the mechanical strength, antibacterial properties, and adhesion of hydrogels but also achieve sustained drug release. From the perspective of clinical application, these characteristics are significant for wound healing. The combination of nanomaterial and hydrogel is an ideal dressing with broad application prospects for wound healing in the future.
Highlights
A skin wound, one of the most common clinical diseases, is defined as damage to the structure or integrity of skin tissue due to various causes [1,2,3,4]
We summarize the latest developments of nanohydrogel dressings and their application prospects in wound healing, and we further analyze the current opportunities and challenges in wound healing
Li et al researched and prepared a nanocomposite scaffold composed of polyethylene glycol diacrylate (PEGDA), forming the main network, and a secondary dynamic network (PABC scaffold) formed between copper-containing bioactive glass nanoparticles (BGNC) and sodium alginate (ALG)
Summary
A skin wound, one of the most common clinical diseases, is defined as damage to the structure or integrity of skin tissue due to various causes [1,2,3,4]. A moist wound dressing can create and maintain a moist environment around the wound and promote the regeneration and repair of the dermis and epidermal tissue during the wound healing process. Hydrogel dressings can provide a moist healing environment and speed up the wound healing time [8]. They have the advantages of good biocompatibility, strong water absorption, less bacterial growth, and (a). We summarize the latest developments of nanohydrogel dressings and their application prospects in wound healing, and we further analyze the current opportunities and challenges in wound healing
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