Application of Nano Drug Carrier in the Detection of Human Hemoglobin Content

Abstract

This paper studies the application of nano drug carrier in the detection of human hemoglobin content. Taking nano modified electrode as nano drug carrier, the application of nano silver particle modified silver electrode and nano poly thionine modified electrode in the detection of human hemoglobin content is studied. Atomic force microscope, UV-Vis and FT-IR are used to characterize the nano poly(thionine), and the electrochemical properties of nano poly(thionine) modified electrode. The silver electrode decorated with nano silver particles is made. The electrochemical behavior of hemoglobin on the modified electrode is studied. The experimental results show that a pair of redox peaks appear in the silver electrode modified by nano silver particles. With the increase of Hb concentration, the redox peak current in the cyclic voltammogram of the silver electrode modified by nano silver particles increases correspondingly, and the hemoglobin has a good current response on the silver electrode modified by nano silver particles, which is a kind of adsorption current. The electrochemical activity of nano poly thionine shows a decreasing tendency with pH value. After adding hemoglobin, there is a significant reduction peak near –0.4 V. With the increase of hemoglobin concentration, the reduction peak current increases accordingly. The nano poly thionine modified electrode has a catalytic effect on the reduction of hemoglobin. The results show that the two nano drug carriers, nano poly thionine modified electrode and nano silver particle modified silver electrode, can effectively analyze and determine human hemoglobin.