Abstract

There are several kinds of Chinese herbal medicines originating from diverse sources. However, the rapid taxonomic identification of large quantities of Chinese herbal medicines is difficult using traditional methods, and the process of identification itself is prone to error. Therefore, the traditional methods of Chinese herbal medicine identification must meet higher standards of accuracy. With the rapid development of bioinformatics, methods relying on bioinformatics strategies offer advantages with respect to the speed and accuracy of the identification of Chinese herbal medicine ingredients. This article reviews the applicability and limitations of biochip and DNA barcoding technology in the identification of Chinese herbal medicines. Furthermore, the future development of the two technologies of interest is discussed.

Highlights

  • The traditional method of determining the authenticity of traditional Chinese medicine is to evaluate the color, shape, or nature of the medicinal materials using either physical/chemical methods or microscopy

  • It is assumed that there is a certain level of contamination of counterfeit and inferior medicinal ingredients in compound medications made by processing drugs of many ingredients, and it is difficult to identify the contaminating materials following the traditional method of identification

  • With the broad applicability of these techniques, we hope that the identification of Chinese herbal medicines can be further developed

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Summary

Introduction

The traditional method of determining the authenticity of traditional Chinese medicine is to evaluate the color, shape, or nature of the medicinal materials using either physical/chemical methods or microscopy. Molecules 2018, 23, 2728 data, and so on, in order to identify and solve specific problems At present, this technology has been applied to many fields, including Chinese herbal screening, as described in this review. It has been applied to other medical fields, such as studying the effect of a drug on the prevention and treatment of diseases, and studying special drugs for cancer cell proliferation and death [9] It is of great significance and value for Chinese medicine modernization to further study the identification of Chinese herbal medicines by bioinformatics. This review discusses the promotion and use of bioinformatics in the field of Chinese herbal medicine identification in recent years, and compares the advantages and disadvantages of various methods. With the broad applicability of these techniques, we hope that the identification of Chinese herbal medicines can be further developed

Biochip Technology
Gene Chip
Protein Chip
DNA Barcoding
Mitochondrial
Ribosomal DNA Barcode
DNA Barcode Combination Identification
The Limitations of DNA Barcoding
Findings
Future Perspectives
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