Abstract

Objective To discuss the safety and clinical efficacy of modified traction method using endoloop and clip for endoscopic submucosal dissection(ESD). Methods Fifty patients who underwent ESD at Renmin Hosptial of Wuhan University between August 2016 and February 2017 were randomly divided into two groups, including 25 patients in modified ESD group and 25 patients in conventional ESD group as control. The therapeutic conditions, dissection time and incidence of complications were compared between the two groups. Results In the modified ESD group, the dissection time of submucosal exposure to the full dissection (19.9±6.5 min VS 26.4±9.2 min, P=0.001), total dissection time (27.5±8.1 min VS 35.1±10.7 min, P=0.003), and dissection time per unit area (2.4±1.1 min/cm2 VS 3.3±1.3 min/cm2,P=0.009) were significantly shorter compared with those in the control group. There were 1 case of delayed bleeding in the modified group and 2 cases in the control group with no significant difference (P=0.248). No perforation occurred. Conclusion The modified traction method using endoloop and clip for ESD is safe and effective with a shorter operation time. Key words: Endoscopes, gastrointestinal; Safety; Endoscopic submucosal dissection; Traction; Dissection time

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