Abstract
The mixed methods research is the third research method following quantitative study and qualitative study which plays an unique role in nursing research. This paper reviewed the application of mixed methods research in nursing research and expounded the design flow of the mixed methods research based on explanatory sequential design as well as the key questions during combining quantitative study with qualitative study. Key words: Review; Mixed methods research; Nursing; Explanatory sequential design; Combination of quality and quantity
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