Abstract
IntroductionThe objective of this study was to investigate the effect of mivacurium in the application of fast-track anesthesia for transthoracic device closure of ventricular septal defects (VSDs) in children.MethodsThe data of 108 children who underwent transthoracic device closure of VSDs from December 2018 to June 2020 were recorded and analyzed. All children were divided into group M (mivacurium group, n=55) and group C (cisatracurium group, n=53) according to the different muscle relaxant drug used.ResultsNo statistically significant differences in general preoperative data, intraoperative hemodynamic changes, or the incidence of adverse reactions were noted between the two groups (P>0.05). However, the intubation condition rating of children in group M was better than that in group C. The onset time, duration of clinical action and recovery index of the muscle relaxant, postoperative mechanical ventilation duration, and length of intensive care unit stay in group M were significantly lower than those in group C (P<0.05).ConclusionIt is safe and feasible to use mivacurium as a muscle relaxant in children undergoing fast-track cardiac anesthesia during transthoracic device closure of VSDs.
Highlights
The objective of this study was to investigate the effect of mivacurium in the application of fast-track anesthesia for transthoracic device closure of ventricular septal defects (VSDs) in children
Transthoracic device closure of VSD guided by transesophageal echocardiography (TEE) combined with fast-track cardiac anesthesia technology may promote the rapid postoperative recovery of patients[4,5]
This study aimed to investigate the effect of mivacurium in fast-track cardiac anesthesia for transthoracic device closure of VSDs in children
Summary
The objective of this study was to investigate the effect of mivacurium in the application of fast-track anesthesia for transthoracic device closure of ventricular septal defects (VSDs) in children. Used treatments include surgical repair under cardiopulmonary bypass and transcatheter device closure guided by echocardiography and fluoroscopy. Transthoracic device closure of VSD has been widely used in the treatment of VSD and accepted by children and their families given its small incision, lack of a need for cardiopulmonary bypass, lack of radiation exposure, short operation time, fast postoperative recovery, and few complications[2,3]. Transthoracic device closure of VSD guided by transesophageal echocardiography (TEE) combined with fast-track cardiac anesthesia technology may promote the rapid postoperative recovery of patients[4,5]. Many studies on fast-track cardiac anesthesia have focused on the use of opioids but ignored the choice of muscle relaxants. The reasonable choice of muscle relaxants is another key to
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