Abstract
The capability of FT-IR transmission spectrometry was examined for the direct determination of glucose in whole blood without any sample preparation. For these investigations, the whole blood samples were automatically aspirated by a syringe pump into the transmission cell. Infrared spectra were recorded in the 1500–900 cm−1 range. Despite the high water background absorption and the complex blood matrix, significant spectral changes due to different glucose concentrations were observed. Chemometric (partial least-squares) models were applied for the determination of glucose. A standard error of calibration of 13.8 mg/dL was obtained by using a partial least-squares calibration model containing five ranks. The residues for an independent test set were less than 15 mg/dL.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
