Application of mechanical pleurodesis in uniportal video assisted thoracoscopic surgery for the treatment of primary spontaneous pneumothorax

Abstract

Objective To investigate the feasibility and effect of mechanical pleurodesis in the treatment of primary spontaneous pneumothorax（ PSP）by uniportal video assisted thoracoscopic surgery（UVATS）. Methods From October 2010 to May 2013,58 patients with PSP received UVATS and mechanical pleurodesis during the operation,at the same time,58 patients with PSP re-ceived pleural fixation with talcum powder. The clinical indexes including operation time,blood loss volume during operation,postoperative body temperature,postoperative amount of drainage,pain degree, elevated level of white blood cells,drainage tube duration,hospitalization duration was observed. Re-sults Compared with the talcum powder group,the mechanical pleurodesis group had significantly fewer cases of postoperative fever（ ﹥38. 0 ℃）[ 10 cases（ 17. 2%）vs 44 cases（ 75. 8%）,χ2 =40. 052 ,P=0. 0001]and abnormal WBC level（ ﹥10 ×109）[9 cases（15. 5%）vs 41 cases（70. 6%）,χ2 =35. 995, P=0. 0001],fewer chest drainage volume[（325 ± 72）ml vs（655 ± 76）ml,t=24. 006,P=0. 0001], lower pain score[（1. 6 ± 0. 7）vs（5. 3 ± 0. 5）,t=32. 756,P=0. 0001],shorter drainage tube duration [（24 ± 3. 5）h vs（36 ± 7. 3）h,t=11. 288,P =0. 0001]and hospital stays[（3. 0 ± 0. 7）d vs（4. 8 ± 1. 2）d,t=9. 867,P=0. 0001]. Conclusions Mechanical pleurodesis is superior to other pleurodesis in uniportal video assisted thoracoscopic surgery（ UVATS）for the treatment of primary spontaneous pneu-mothorax（ PSP）. It is safe and feasible,also can reduce the complications caused by operation,and the curative effect is ideal. Key words: Mechanical pleurodesis Uniportal video assisted thoracoscopic surgery Primary spontaneous pneumothorax