Application of Measured Hypercapnic-Hypoxic Patients Breathing Protocols in Rehabilitation of Asthmatic-Hypertensive Female Patients

Abstract

Background Although combination of asthma and arterial hypertension in Caucasian females is not a rare condition its significance is under-evaluated. The aim of the study was to evaluate the special measured hypercapnic-hypoxic breathing protocols effects on respiratory system functional state in asthmatic female patients with essential hypertension. Method Research protocol included observation of 70 female patients with mild asthma combined with mild essential hypertension, from 32 to 52 years old (mean 42.15±3.87) who formed the 1st (research) group. Control group (2nd) included individuals, who were not suffering from any chronic respiratory disease in anamnesis, but have mild essential hypertension. Hypercapnic-hypoxic breathing protocols were based on measured breathing exercises with different length of breathing phases: inhalation, exhalation, holding patients’ breath with retention of the breath on expiration phase (3–4 seconds). Breathing exercises were administered under control of oxygen and carbooxygen partial blood pressure, exhaled air gases chronometric analysis, individual patient’s perceptibility to the hypercapnia and hypoxia levels during 6–8 weeks, for 20 min 3 times per day using special facility. Parameters of the respiratory system function were examined by the method of computer spirography (Jaeger®,Germany) before and after the course of measured breathing exercises administration. Results Before hypercapnic-hypoxic breathing protocol administration such predictive and active parameters of computer spirography as Maximum Voluntary Ventilation (MVV), Forced Vital Capacity (FVC), Forced Expiratory Volume after 1 s (FEV 1). FEV 1 as % of lnspiratory Vital Capacity (FEV 1%VCIN), FEV 1 as % of FVC (FEV 1 E), and Peak lnspiratory and Expiratory Flow (PIF, PEF) were evaluated and it was found that they were significantly lower in 98% of the 1st group patients (p Conclusion Thus, administration of the measured hypercapnic-hypoxic breathing protocols in hypertensive-asthmatic female patients’ rehabilitation is a cost-effective method for significant improvement of the respiratory functional state active parameters.