Abstract
The aim of this study was to investigate a role of adrenal function stimulation in patients with stage 3 chronic obstructive pulmonary disease (COPD). Methods . Blood levels of cortisol, aldosterone and testosterone were measured in 82 males with severe COPD and in 25 healthy subjects. The study involved three patient groups: 41 patients with stage 3 COPD who received lowintensity infrared laser radiation with a frequency of 80 Hz applied on the adrenal gland area additionally to the standard therapy; 26 patients with stage 3 COPD who received standard therapy only and 15 patients with COPD who received standard therapy and a placebo exposure using a switched off laser device. Results . A significant reduction in blood cortisol, aldosterone and testosterone levels in patients with stage 3 COPD was found. A role of adrenal function stimulation was confirmed in patients with stage 3 COPD. Conclusion. Severity of adrenal hormonal disorders correlates directly to severity of COPD. Treatment of male patients with stage 3 COPD should include adrenal hormone correction using both medication and nonmedication on individual basis. The lowintensity laser radiation of adrenal area could significantly increase blood cortisol level and improve quality of life of the patients.
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