Application of laparoscopic-assisted total gastrectomy combined with D2 lymph node dissection for advanced gastric cancer

Abstract

Objective To investigate the clinical effect of laparoscopic-assisted total gastrectomy (LATG) combined with D2 lymph node dissection in the treatment of advanced gastric cancer. Methods 70 patients with advanced gastric cancer who underwent surgery in our hospital from May 2015 to May 2018 were analyzed retrospectively. They were divided into the laparoscopic group (39 cases who received LATG combined with D2 lymph node dissection) and the laparotomy group (31 cases who received laparotomy). SPSS21.0 software was used for statistical analysis. Intraoperative and postoperative indicators and serological related indicators before and after surgery were expressed by (±s), and examined by t test. Postoperative complications were analyzed by χ2 test. P<0.05 had significant difference. Results The operation time of the laparoscopic group was longer than that of the laparotomy group (P 0.05). Before operation, there was no significant difference in WBC, N, Cor and CRP levels between the two groups (P>0.05); on the 1st, 4th and 7th day after operation, the indexes were significantly higher than those before operation (P 0.05). Conclusion LATG combined with D2 lymph node dissection for advanced gastric cancer has the advantages of less trauma and less stress reaction. Key words: Stomach neoplasms; Laparoscopes; Gastrectomy; Lymph node excision