Application of IQQA three-dimensional reconstruction technique in precise laparoscopic or robot-assisted laparoscopic partial nephrectomy for renal hilar tumors

Abstract

Objective To evaluate the feasibility and effectiveness of the application of IQQA (Intelligent/interactive Qualitative and Quantitative Analysis) three-dimensional reconstruction technique in precise laparoscopic or robot-assisted laparoscopic partial nephrectomy (LPN or RAPN) for renal hilar tumors. Methods The study retrospectively reviewed 11patients with hilar tumors from February 2016 to February 2017. Of the 11 patients, 4 were women and 7 were men, with an average age of 51 years (range 38 to 70 years). The average tumor size was 3.1 cm (range 1.7 to 4.3 cm). For tumor stage, 9 patients were in T1a stage and 2 patients were in T1b stage. The average R. E.N.A.L score was 8.7 (range 7 to 10). The mean preoperative GFR was 40.6 ml/min (range 32 to 45 ml/min). IQQA three-dimensional reconstruction technique was applied for the purpose of precise navigation and resection of the tumors. Multivariate analysis was used to identify predictors of warm ischemia time, estimated blood loss, major perioperative complications, and postoperative renal function. Results All 11 laparoscopic or robot-assisted laparoscopic hilar partial nephrectomies were successfully completed without conversion to a hand-assisted or an open approach. Under the navigation of IQQA, all tumors were found precisely at the first time during surgeries. The final pathologic examination revealed that all the 11 patients were clear cell renal cell carcinomas. The mean operative time was 142 minutes (range 90 to 230 minutes), with a mean warm ischemia time of 24 minutes (range 17 to 33 minutes). The estimated blood loss was 146 ml (range 50 to 400 ml). No intraoperative complications occurred. Two patients suffered from postoperative complications. One patient with gross hematuria was recovered by consistent bladder irrigation. The other patient with postoperative hemorrhage needed transfusion. All patients had negative margins on the final pathologic examination. At a mean follow-up period of 3 months, the mean GRR is 22.5 ml/min (range 13 to 34 ml/min) without any disease recurrence. Conclusions With peculiar features, such as accurate location, complete resection and fewer perioperative complications, the application of IQQA three-dimensional reconstruction technique in precise partial nephrectomy represents a safe and effective procedure for hilar tumors. Key words: Renal cell carcinoma; Renal hilar tumor; Partial nephrectomy; Three-dimensional reconstruction; Surgery navigation