Abstract

60Co-gamma-rays can be used efficiently for sterilizing products, such highly refined ones as drugs, vaccines, biochemicals. Examples of advanced stage application are: sterilization of enzymes used for food production and of supplements for drug manufacture. As economical aspects are of growing importance also for production of vaccines and antigens for diagnostic purposes, methods should take into account quantitative factors and qualitative biological properties. Therefore cautious inactivation of microorganisms incl. viruses is demonstrated. Special problems of irradiation are discussed.

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