Abstract
Objective To evaluate the effects of ultrahigh-field intraoperative magnetic resonance imaging (iMRI) in combination with function neuronavigation on extent of resection of insular glioma and postoperative neurological function. Methods Thirty-eight patients with insular glioma who received iMRI in combination with functional neuronavigation surgery were enrolled between January 2013 and April 2014. The extent of resection and postoperative complications were evaluated. Results Residual tumors in 20 patients (53%) were found by iMRI. They were removed again in 17 patients after scanning. After further resection, the residual tumor volume was decreased from 17.9 ml to 1.1 ml (P=0.0002). The extent of resection increased from 96.9% to 99.2% (P=0.0013). 24% of patients had neurological dysfunction after procedure. Conclusion iMRI in combination with functional neuronavigation surgery is safe and effective. It significantly increases the extent of resection of insular glioma and protects neurological function. Key words: Monitoring, intraoperative; Magnetic resonance imaging; Neuronavigation; Glioma; Microsurgery
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