Abstract
The process of Medical image registration is essentially to find a optimal transformation between two medical images, Because of the advantages and disadvantages of various optimization algorithm is relative, this paper proposed by the simplex algorithm and genetic algorithm hybrid optimization algorithm combining for registration parameter optimization, analysed and compared with the traditional genetic algorithm through experiment, verify the simplex genetic algorithm whether in registration precision or in registration efficiency are obviously better than the traditional genetic algorithm, Is a kind of practical optimization algorithm.
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