Abstract
We study a one dimensional non-linear model of multi-layered human skin exposed to microwave heating during cancer therapy. The model is analyzed using homotopy perturbation method and the fact that there are variations in specific heat, thermal conductivity and blood perfusion from one individual to another were considered. The purpose of this study was to investigate the effect of variable blood perfusion, microwave heating and thermal conductivity on the temperature field during microwave hyperthermia. By varying the parameters, we were able to determine maximum rise of temperature as an individual undergoes cancer therapy. The results were presented in graphs and it was discovered that the temperature of the tumor increases with increase in the microwave heating index while the blood perfusion remain constant.
Highlights
IntroductionHyperthermia (or thermotherapy) is a cancer treatment that involves heating tumor cells within the body
Hyperthermia is a cancer treatment that involves heating tumor cells within the body
OF FINDINGS In this study, we examined the effect of parameters on temperature rise during microwave hyperthermia
Summary
Hyperthermia (or thermotherapy) is a cancer treatment that involves heating tumor cells within the body. Elevating the temperature of tumor cells results in cell membrane damage, which in turn leads to the destruction of the cancer cells. Hyperthermia treatment of cancer requires directing a carefully controlled dose of heat to the cancerous tumor and surrounding body tissue. Hyperthermia treatment is an important therapeutic option in biomedical cancer medicine. It is promising method to treat various types of cancer by heating the tumor to about 410C using electro-magnetic energy, thereby inducing preferential opoptosis of cancerous cells. It makes the tumor more susceptible to an accompanying radio or chemotherapy (Christen and Shenk, 2007)
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