Application of hippocampotomy in surgery of intractable occipital epilepsy

Abstract

Objective o analyze the surgical outcome and experience of the combination of cortex resection and hippocampotomy for surgical treatment of intractable occipital epilepsy.Methods 20 surgical cases of occipital epilepsy with conducting to hippocampus were studied retrospectively.The patient'S general clinical data,seizure features,surgical outcomes and surgical experiences were studied.There were 17 cases (85%)under partial seizures and secondary general tonic-clonic attack,9 patients with temporal aures or automasim,9 cases with temporal abnormal metabolizing in PET imaging and 13 cases with abnormal in MRI or MRS imaging in hippocampus.Epileptogenics Was located in lateral occipital lobe in 8 cases(40%),temporo-occipital lobe in 6 cases(30%)and mesial occipital lobe in 6 cases.All patients were performed the operation of combination of occipital cortex resection and hippocampotomy.Results The surgical results included 16 Engle I cases.2 II case and 2Ⅲgrade cases.Conclusion Intractable occipital epilepsy with conducting to hippocampus always has temporal aures or automasim and abnormal image of temporal lobe.The operation of the combination of occipital cortex resection with hippocampotomy could achieve good surgicat outcome. Key words: Epilepsy surgery; Hippocampotomy; Intractable occipital lobe epilepsy; Clinic feature; Outcome