Application of exogenous enzymes: is digestibility an appropriate response variable?

Abstract

The use of digestible nutrient values for feedstuffs and non-ruminant diets has resulted in significant improvements in ingredient utilisation, pig and poultry performance and efficiency, and reduced feed costs and environmental waste. The use of exogenous enzymes such as carbohydrases, phytases and proteases in non-ruminant diets has also had a profound effect on meat production, feed efficiency and reduced environmental waste through an improvement in nutrient digestibility. However, the use of nutrient digestibility in the absence of animal growth or efficiency, on individual feed ingredients or complete diets, as an estimate of exogenous enzyme efficacy requires careful consideration. Numerous studies have highlighted a range of factors that will influence the estimated digestibility coefficients. These include but are not limited to: differences in methods employed, the use of a point-in-time measure of nutrient digestion versus growth over the lifetime of the chicken or pig, adjustment (or not) for endogenous losses, age of the animal, production status and nutritional status of the diet. These factors can also be influenced by or have an influence on exogenous enzyme efficacy to yield positive, negative, non-significant, or inconclusive effects on nutrient digestion. In addition, exogenous enzyme supplementation of diets has resulted in improvements in nutrient digestibility in the absence of an effect on productivity or efficiency or vice versa. Therefore, the use of nutrient digestibility as a response variable for exogenous enzyme efficacy is informative but only in the presence of growth performance, intake, or meat yield.