Abstract
In the near future, powerful X-ray source (Synchrotron Orbital Radiation, SOR) will be available at National Laboratory for High Energy Physics (Tsukuba). One of the most promising researches using SOR system is its application to biomedical problems. The objective of this report is to review the EXAFS studies on biological system. EXAFS can probe the local structure just around the X-ray absorbing atom. In this paper we describe the analysis of EXAFS spectrum of iron atom in rubredoxin, one of the simplest metalloproteins, and then we summarize the results of structural analysis on various metallo-proteins and enzymes such as nitrogenase, cytochrome P-450, hemoglobin, cytochrome c oxidase and so on.
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