Application of dimeric orthopalladated complex in Suzuki–Miyaura cross coupling reaction under microwave irradiation and conventional heating

Abstract

The Suzuki–Miyaura reaction of various aryl halides using [Pd{C 6H 2(CH 2CH 2NH 2)–(OMe) 2,3,4} (μ-Br)] 2 have been investigated. This orthopalladated complex is an efficient, stable and non-sensitive to air and moisture catalyst for the hetrocoupling reaction in DMF as the reaction solvent at 130 °C. The combination of dimeric complex as homogenous catalyst and microwave irradiation can be very useful and efficient methods in organic synthesis, so the application of microwave irradiation have been investigated using homogenous dimeric complex [Pd{C 6H 2(CH 2CH 2NH 2)–(OMe) 2,3,4} (μ-Br)] 2. Application of dimeric complex as catalyst caused to produce the desired coupling products and the using of microwave irradiation improving the yields of the reactions and shortening the reaction times.