Abstract

Schizophrenia is a debilitating neurological and psychiatric disorder that can result in severe disability for those affected. The presence of this disorder can have far-reaching effects on all aspects of a person's life, affecting not only their personal and familial relationships, but also their social interactions, academic pursuits, and career prospects. Some individuals with schizophrenia may experience multiple cycles of symptom exacerbation and remission throughout their lifetime, with symptoms worsening and improving intermittently. However, for others, symptoms may progressively worsen over time and may even become increasingly severe, potentially persisting throughout their lifetime and significantly impacting their daily life and social relationships. As of today, most medications are still not perfect treatments for this disorder. And only a few, such as lumateperone, have shown initial success in improving and relieving patients' negative symptoms and cognitive dysfunction. In addition, psychological therapies are being developed, but therapists and psychiatrists are still limited in the number of treatments available. In the face of these unresolved challenges, different treatment methods have been conducted to evaluate investigational therapies, and new models are being constructed to study new pharmacological molecular therapeutic pathways. This research provides an overview of some of the current mainstream treatment strategies for schizophrenia and an outlook for the future.

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