Abstract

Chronic diseases represented by circulatory diseases have gradually become the main types of diseases affecting the health of our population. Establishing a circulatory system disease prediction model to predict the occurrence of diseases and controlling them is of great significance to the health of our population. This article is based on the prospective population cohort data of chronic diseases in China, based on the existing medical cohort studies, the Kaplan–Meier method was used for feature selection, and the traditional medical analysis model represented by the Cox proportional hazards model was used and introduced. Support vector machine research methods in machine learning establish circulatory system disease prediction models. This paper also attempts to introduce the proportion of the explanation variation (PEV) and the shrinkage factor to improve the Cox proportional hazards model; and the use of Particle Swarm Optimization (PSO) algorithm to optimize the parameters of SVM model. Finally, the experimental verification of the above prediction models is carried out. This paper uses the model training time, Accuracy rate(ACC), the area under curve (AUC)of the Receiver Operator Characteristic curve (ROC) and other forecasting indicators. The experimental results show that the PSO-SVM-CSDPC disease prediction model and the S-Cox-CSDPC circulation system disease prediction model have the advantages of fast model solving speed, accurate prediction results and strong generalization ability, which are helpful for the intervention and control of chronic diseases.

Highlights

  • Cohort research has great advantages in revealing the risks and trends of chronic diseases

  • We conducted circulatory disease prediction studies based on data from China’s chronic disease prospective research project, to improve traditional algorithms used in medical research, and to use artificial intelligence machine learning algorithms to make the research algorithms better applicable to population cohorts

  • The China Kadoorie Biobank (CKB) [3] was a large-scale chronic disease initiated by the China

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Summary

Introduction

Cohort research has great advantages in revealing the risks and trends of chronic diseases. Algorithms 2018, 11, 162 reliable sample of local cohort data collected It can provide basic data support for the study of etiology, disease trend and disease prediction of chronic diseases represented by circulatory system. We conducted circulatory disease prediction studies based on data from China’s chronic disease prospective research project, to improve traditional algorithms used in medical research, and to use artificial intelligence machine learning algorithms to make the research algorithms better applicable to population cohorts. We obtained the correlation between exposure factors and outcomes in Chinese chronic disease prospective research project data based on the single factor analysis model in a population cohort study and survival analysis. According to the contraction prediction theory, we constructed the optimization model which is S-Cox-CSDPC disease prediction model; (c) By analyzing the impact of various parameters in the training process of SVM-CSDPC disease prediction model, combined with particle swarm optimization algorithm, we constructed the optimization model PSO-SVM-CSDPC disease prediction model

CKB Data
Basic Theory
Shrinkage Prediction Theory
Support Vector Machine
Particle Swarm Optimization Algorithm
Cox-CSDPC Disease Prediction Model
S-Cox-CSDPC Disease Prediction Model
SVM-CSDPC Disease Prediction Model
PSO-SVM-CSDPC Disease Prediction Model
Model Evaluation Indicators
ROC Curves
Yoden Index
Experimental Framework
Cox-CSDPC Disease Prediction Model Application and Results Analysis
S-Cox-CSDPC Disease Prediction Model Application and Results Analysis
SVM-CSDPC Disease Prediction Model Application and Results Analysis
PSO-SVM-CSDPC Disease Prediction Model Application and Results Analysis
Compare with Existing Model Application Results
Conclusions
Full Text
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