Abstract
Clustered Regularly Interspaced Short Palindromic Repeat CRISPR-associated Nuclease(CRISPR/Cas)systems are recently discovered, RNA-based immune systems that control invasions of viruses and plasmids in archaea and bacteria.Prokaryotes with CRISPR/Cas immune systems capture short invader sequences within the CRISPR loci in their genomes, and small RNAs produced from the CRISPR loci guide Cas9 proteins to recognize and degrade the invading nucleic acids.The CRISPR/Cas9 system is rapidly revolutionizing the field of genetic engineering, allowing researchers to alter the genomes of a large variety of organisms with relative ease, and it can alleviate the disease progression by editing immune cells in immune system. Key words: The CRISPR-Cas9; Gene editing; Immune cells
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