Abstract
Background: Acute cerebral infarction (ACI) is a common cerebrovascular disease that seriously endangers human health. It is very important to carry out disease assessments to rescue patients who may suffer from preventable death. Objectives: This study aimed to explore the predictive value of concomitant disease scoring for the prognosis of patients with ACI. Methods: This is a respective observational study. A total of 399 patients with ACI from the Affiliated Hospital of North China University of Science and Technology, who met the inclusion criteria, were enrolled in the present study. The concomitant disease score was assessed within 24 hours after admission, and the risk degree of death was analyzed. Then, the goodness of fit test and validity analysis were carried out, and the best survival/death cut-off value was determined. Results: The area under the receiver operating characteristic (ROC) curve for the concomitant disease score was 0.700, the distinctiveness was relatively good, and the prediction cut-off value was 10 points. Furthermore, the mortality rate of patients with a higher score was significantly higher compared to patients with a lower score. Conclusions: The concomitant disease score has good predictive value for the prognosis of ACI patients, and is an ideal system for evaluating the condition of cerebral infarction.
Highlights
This study aims to explore the predictive value of concomitant disease scoring for the prognosis of patients with acute cerebral infarction (ACI)
Cerebral infarction is a hypoxic and ischemic necrosis induced by insufficient blood supply of the local brain, which results from a blockage or narrowing in the arteries, and the blockage can be due to a thrombus, an embolus or an atheromatous stenosis of one or more arteries.[4,5]
All included patients were admitted to the hospital within three days after onset, met the diagnostic criteria established at the Fourth National Cerebrovascular Disease Conference of China, and were confirmed by craniocerebral computed tomography (CT) or magnetic resonance imaging (MRI)
Summary
This study aims to explore the predictive value of concomitant disease scoring for the prognosis of patients with acute cerebral infarction (ACI). The goodness of fit test and validity analysis were carried out, the best survival/death cut-off value was determined, and its predictive value for the prognosis of ACI patients was assessed. Conclusion: This concomitant disease score has good predictive value for the prognosis of ACI patients, and is an ideal system for evaluating the condition of cerebral infarction. It is very important to carry out disease assessment to rescue patients who may suffer from preventable death.[7] In the present study, the concomitant disease score of patients with ACI was assessed to preliminarily investigate its effect on the prognosis of ACI, which is beneficial for doctors to make timely and effective intervention measures
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