Abstract

Background and Objective: Clinical effect is necessary for the inheritance and development of traditional Chinese medicine (TCM). The conventional single primary outcome evaluation method is difficult to reflect the advantages of multi-target and multi-dimensional treatment of TCM. The comprehensive evaluation method can combine multiple dimensional outcomes such as Western medicine-related outcomes, TCM-related syndromes, and patient report outcomes into a single-dimensional comprehensive outcome, which can reflect the advantages of the multi-dimensional efficacy of TCM, and has been gradually applied to the clinical efficacy of TCM in recent years. In this study, we aimed to introduce comprehensive evaluation methods and guide TCM researchers use these methods correctly, then provide methodological aid for the comprehensive and objective evaluation of true clinical effect of TCM.

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