Application of central composite design for methyl red dispersive solid phase extraction based on silver nanocomposite hydrogel: Microwave assisted synthesis

Abstract

In this study microwave irradiation was used to synthesis the silver nanocomposite hydrogel and the usefulness as an adsorbent for the preconcentration, extraction and determination of methyl red (MR) from water by dispersive solid phase extraction method was evaluated. For this purpose, silver nanocomposite hydrogel (SNH) was synthesized and characterized by thermo-gravimetric (TG) analysis, FT-IR, TEM and SEM images. The effects of some important variables such as centrifuge time (min), the pH of the methyl red solution, amount of adsorbent (g), acetone volume (mL) and chloroform volume (mL) on methyl red removal were studied using central composite design (CCD) and the optimum experimental conditions were evaluated by the desirability function (DF) combined response surface methodology (RSM). Under the optimal experimental conditions, the detection limit was found to be 1.4μgmL−1 for MR adsorption. The limit of quantification and the linear range of calibration curve were 4.6μgmL−1 and 0.1–25μgmL−1, respectively.