Application of biologically active substances from marine hydrobionts in the treatment of age-related macular degeneration

Abstract

Aim. To evaluate the effectiveness of products obtained from marine aquatic organisms in the treatment of age-related macular degeneration (AMD).Methods. In total, 90 patients diagnosed with AMD of various stages were examined. The control group (30 people) received a vitamin-mineral complex containing carotenoids – lutein and zeaxanthin (Retinorm). The 2nd group of patients (30 people) received the Scallop Extract product. The 3rd group of patients (30 people) received the Ascidia Oil Extract in combination with the basic therapy. All patients underwent a comprehensive ophthalmological examination, including optical coherence tomography of the macula and perimetry. The examination was carried out prior to and two weeks after treatment completion.Results. The experimental group of patients receiving Scallop Extract showed a significant increase in visual acuity indicators after treatment completion. For comparison, the experimental groups of patients receiving Ascidia Oil Extract demonstrated improved photosensitivity indicators and reduced visual field defects.Conclusions. Addition of marine hydrobiont-based products to the basic AMD therapy is pathogenetically justified due to its positive effects on the maintenance and improvement of visual functions, as well as the light sensitivity of the retina.