Application of bearing test combination in sensorineural deafness with hyperbaric oxygen treatment

Abstract

Objective To study the relationship between the cochlear hair cell and sensorineural deafness, so as to explore hearing test method for early intervention and discovery. Methods Two hundred and fifty-three patients suffered from sensorineural deafness with hyperbaric oxygen （HBO） treatment were randomly seteceted, curative effect before and after HBO treantment were recorded and compared, respectively. Examinations of acoustic brainstem evoked respone （ABR） and distortion product otoacoustic emission （DPOAE） were conducted for the evaluation of hearing test result. Results It was revealed that total effective rate of mild hearing loss after two courses of HBO treatment was significantly higher than that of moderate deafness. There was significant difference in the incidence of abnormal ratio of ABR between pretherapy and aftertherapy of HBO （ P 〈 0.05 ）. DPOAE amplitude obviously decreased after one and two courses of HBO treatment. At 1.4-6.0 kHz frequency before and one course of HBO treatment, there was a slight upward. Conclusions HBO may have therapeutic efficacy on sensorineural deafness by revive the activity of cochlear hair apoptosis cell. DPOAE is more sensitive and prospective than ABR. The combination of ABR and DPOAE can be used to judge the degree of hearing impairment and recovery. Key words: Cochlear hair cell; Sensorineural deafness ; Hyperbaric oxygen; Acoustic brainstemevoked response; Distortion product otoacoustic emission