Abstract
BackgroundThe aim of this study is to evaluate in-house antibiotic use in a state hospital in Turkey with its cost, using the ATC/DDD index, which is an accepted standard method.MethodsThis study was performed as a point prevalence study in a state hospital with 372 beds. All in-house patients using antibiotics on July 19, 2011 were included in the study. Indications for antibiotic use and information about the patients were recorded on special forms. Antibiotic use and cost analysis were evaluated using the ATC/DDD index, which is also suggested by the WHO to be used in similar studies.Findings147 patients out of 308 patients who were in-house were identified to use antibiotics with appropriate indications for prophylaxis or treatment in 61% of the patients. The rate of appropriate antibiotic use was identified to be in 78%, while this rate was 38.9% in surgical clinics. The daily cost of the antibiotics consumed on the date of the study was calculated as 4104.79 TL (=2476.80 USD).DiscussionThe rate of inappropriate use of antibiotics seems to be high in our hospital. This will result in both increased costs and also increased nosocomial infection rates with resistant species. Infectious disease specialists should take more active roles in the in-house antibiotic use, hospitals should prepare and implement their own principles of antibiotic use, and microbiology laboratories should be used more effectively. These measures would decrease the conspicuous shortcomings in the antibiotic use.
Highlights
As the anti infective agents are most frequently used group of drugs in our country, doctors most frequently error when chosing them [1,2]
The rate of inappropriate use of antibiotics seems to be high in our hospital
This will result in both increased costs and increased nosocomial infection rates with resistant species
Summary
As the anti infective agents are most frequently used group of drugs in our country, doctors most frequently error when chosing them [1,2]. Improper use of antibiotics often lead to many problems such as; development of resistance to antibiotics, negative effects on the ecological balance, side effects on patients, triggering of superinfections and increase in treatment costs [3,4,5]. The most important feature that separates antibiotics from other drugs is that their improper use does negatively affect patients and has negative impact on the hospital microbial environment. While infections caused by resistant microorganisms gradually increase, antimicrobial options used for treating them rapidly diminish [6,7]. In this case, the accurate determination of antibiotic therapy. The aim of this study is to evaluate in-house antibiotic use in a state hospital in Turkey with its cost, using the ATC/DDD index, which is an accepted standard method
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