Abstract
Batten disease is a rare group of neurological diseases, specifically called neuronal ceroid lipofuscinosis. This is a genetic disorder and usually manifests during childhood. Batten disease is fatal and there is currently no proven cure. However, there are certain treatment methods that show potential in mitigating the aftermath of the disease. This review will explore the application and effectiveness of antiepileptic drugs, anticonvulsants, and vitamin C in multiple scenarios to treat Batten disease. Anticonvulsants are a broad group of medications that are used to treat epileptic seizures. Epileptic seizures are a big indicator of Batten disease, making anticonvulsants a potential treatment for Batten disease patients. Antiepileptic drugs also work to stop seizures by decreasing neurological excitation, thus for the same reason are often grouped alongside anticonvulsants and are being investigated as a promising way to help Batten disease patients. Vitamin C helps maintain the integrity of several intracellular processes in the central nervous system, which makes it a possible candidate for treating Batten disease. The known effects of anticonvulsants, antiepileptic drugs, and vitamin C on Batten disease are very limited and should be considered more often by healthcare professionals because of their potential effects on patients with Batten disease.
Highlights
BackgroundBatten disease is a broad cohort of genetic disorders of the nervous system, known as neuronal ceroid lipofuscinosis (NCL) or ceroid lipofuscinosis, neuronal (CNL)
Lower selenium levels in patients were found to correlate to neurological issues similar to Batten disease By taking vitamin C and sodium selenite daily, some abnormalities of Batten disease were reduced in all patients
From all of the data of the experiments incorporated in this piece of literature, it is comprehensible that anticonvulsants can serve as a potential method to expand on our limited knowledge and treatment methods of Batten disease
Summary
Batten disease is a broad cohort of genetic disorders of the nervous system, known as neuronal ceroid lipofuscinosis (NCL) or ceroid lipofuscinosis, neuronal (CNL). Of every 100,000 babies born in the United States (US), two to four have inherited Batten disease from their biological parents [4]. Both males and females have an equal chance of inheriting Batten disease [4,5]
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