Abstract

Hypoxic-ischemic encephalopathy (HIE) is the main reason of causing neonatal death and poor prognosis of the nervous system.The treatment of HIE has gone into the era of therapeutic hypothermia, the early, continuous, specification amplitude integrated electroencephalography(aEEG) monitoring for therapeutic hypothermia to screen appropriate cases, assess early the severity of HIE, provide early nerve protection treatment and evaluate the therapeutic efficiency, early intervention and improve the prognosis of the long-term HIE.This paper review the application of aEEG in the therapeutic hypothermia of HIE. Key words: Hypoxic-ischemic encephalopathy; Therapeutic hypothermia; Amplitude integrated electroencephalography; Infant, newborn

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