Abstract
Lower extremity peripheral arterial occlusive disease poses a unique challenge to traditional angioplasty-based endovascular therapies. Factors that negatively affect the long-term results of percutaneous intervention include the length of the diseased segment, the presence of total occlusion, diabetes mellitus, poor distal runoff, and critical limb ischemia as the clinical presentation. Chronic total occlusion may be present in up to 40 % of patients undergoing treatment for symptomatic peripheral arterial disease, and procedural success rates have historically been lower in the setting of chronic total occlusion. These challenges have spawned the development of a host of new technologies in an attempt to improve the safety and effectiveness of percutaneous revascularization for lower extremity peripheral arterial disease.
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