Abstract

AbstractTo develop insoluble Sn2+ complexes for the preparation of 99mTc radiopharmaceuticals, the adsorption of Sn2+ to macroreticular chelating ion exchange resins having various functional groups was investigated. Among them, a resin containing aminophosphonic acid groups showed a high adsorption capacity for Sn2+, which was bound strongly to the resin by chelation. This macromolecular Sn2+ complex was very stable against hydrolysis and oxidation, and could be applied satisfactorily for the reduction of 99mTc.

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