Application effect of non-invasive proportional assisted ventilation in patients with acute attack of chronic obstructive pulmonary disease

Abstract

Objective To investigate the effect of non-invasive proportional assisted ventilation (PAV) in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) and its effects on oxygen metabolism and lung function. Methods A total of 93 patients with acute exacerbation of COPD in Heji Hospital Affiliated to changzhi Medieal Hospital from March 2016 to March 2018 were divided into two groups by random number table method, 46 patients in PSV group underwent routine pressure support ventilation (PSV), and 47 patients in PAV group were given non-invasive proportion of assisted ventilation. The survival rate and patient hospitalization and ventilator use time and post-treatment oxygen metabolism and lung function of successful patients in the two group were compared. Results In PAV group the hospital stay was (9.45±1.79) d, ventilator use time was (4.49±0.26) d; in the PSV group hospital stay was (13.12±1.68) d, ventilator use time was (5.86±0.32) d, which were significantly shorter than those in the PSV group, the differences were statistically significant (P<0.05). After treatment, The forced expiratory volume for 1 second/forced vital capacity (FEV1/FVC) level (76.13±1.67) and 1 second and expiratory volume as apercentage estimate (FEV1%) (70.68%±2.31%), arterial blood oxygen content [(110.41±5.36)ml/L], oxygen uptake rate (40.28%±2.63%) and treatment success rate (91.49%) in PAV group were higher than those in PSV group [(60.72±3.14), (69.92%±1.23%), (78.59±5.33)ml/L, (27.78%±1.52%), 76.09%], the differences were statistically significant (P<0.05). Conclusions PAV can improve the oxygen metabolism and pulmonary function in patients with acute exacerbation of COPD, improve the success rate of treatment and shorten the hospital stay, and the effect is good. Key words: Non-invasive proportional assisted ventilation; Chronic obstructive pulmonary disease; Acute attack; Oxygen metabolism; Pulmonary function