Abstract
Mosquito-borne diseases are a threat to about half of the worlds population, the harm caused by it has remained serious in recent years. However, traditional methods of insecticide and environmental control have not completely solved the mosquito problem, and many times they come with certain side effects on environment. At the biological and genetic level, it may be possible to find safe and sustainable ways to alleviate the burden of mosquito-borne pathogens. This study focuses on gene editing technology, introducing CRISPR technology and its development, reviewing recent advancements and their applications on kinds of illness like Dengue fever and COVID-19, discussing the future development of mosquito-borne disease control. Moreover, there are several limitations of CRISPR, to solve them, this review presents ideas that the CRISPR system can combine with Digital twin and achieve a better result in experiment. Against the backdrop of rapid developments in artificial intelligence, many cutting-edge technologies are expected to be applied to gene editing in the future.
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