Abstract

Background: Septic shock is a rapidly changing and fatal syndrome that can cause comprehensive deterioration of cardiopulmonary and renal function and multiple organ failure. At the same time, septic shock has the complex clinical manifestations and hemodynamics. PiCCO can accurately monitor blood flow, physical and volume indicators, and active and effective fluid resuscitation are important measures to reduce the fatality rate of septic shock and improve the prognosis of patients. Objectives: To explore the application and nursing of PiCCO in early fluid resuscitation in patients with septic shock. Methods: This was a retrospective observational study. The observation group and the control group each had 30 cases. The observation group used PiCCO to guide fluid resuscitation; the control group used conventional methods to guide fluid resuscitation. The changes in CVP, HR, MAP, and urine volume per hour were observed in the two groups. The changes of various indicators before and after fluid resuscitation, the length of stay in ICU and the mortality rate were compared between the two groups. All the outcomes were collected from the electronic medical case system after patients’ discharge from the hospital. Results: APACHE II, CVP, HR, MAP were compared between the observation group and the control group, and the differences were statistically significant (P 0.05). The blood volume of patients in the observation group was significantly improved after fluid supplementation (P 0.05). Compared with the control group, the length of stay in ICU in the observation group was significantly shorter, and the mortality rate was also significantly reduced (P 0.05). Conclusion: PiCCO can be better used in early fluid resuscitation of patients with septic shock.

Highlights

  • Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection

  • This study explores the application and nursing of Pulse Index Continuous Cardiac Output (PiCCO) volume monitoring in early fluid resuscitation in patients with septic shock, and the report is as follows

  • The comparison of APACHE II score, heart rate (HR), central venous pressure (CVP), MAP between the two groups of patients showed that the difference in APACHE II score, HR, CVP, MAP in the observation group was statistically significant (P < 0.01), and the HR and MAP of the control group were statistically significant (P < 0.05) (Table 1)

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Summary

Introduction

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. Septic shock is a subset of sepsis with circulatory and cellular/metabolic dysfunction associated with a higher risk of mortality and it has always been a problem that plagues the world’s medical community [1] [2] For such patients, a large amount of fluid resuscitation is very important in early treatment. This study explores the application and nursing of PiCCO volume monitoring in early fluid resuscitation in patients with septic shock, and the report is as follows. PiCCO can accurately monitor blood flow, physical and volume indicators, and active and effective fluid resuscitation are important measures to reduce the fatality rate of septic shock and improve the prognosis of patients. Compared with the control group, the length of stay in ICU in the observation group was significantly shorter, and the mortality rate was signifi-

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