Abstract
Ophthalmologists check the condition of the retina by visual examination for signs of retinal disease such as diabetic retinopathy. Typical retinal screening utilizes untunable broadband white light which may not give the best possible visibility of different retinal features-of-interest. Red-free fundus photography applies a green filter in order to enhance blood circulation-related lesions and vascular abnormalities, but the contrast-enhancement is limited to blood-related features. In this study, for enhancing the contrast of various retinal features and lesions in fundus images, a LED-based spectrally tunable light source was constructed and its spectral performance was studied. Optimal illuminants for diabetic retinopathy lesion detection were implemented using the LED-based light source and computational example images were calculated. Retinal lesion visibility (contrast) in retinal images calculated for optimal, red-free and broadband illuminants were compared. The results show that the LED-based optimal illuminants improved the contrast of diabetic lesions in retinal images by 41% compared to the traditional retinal screening. These results are promising and show that light emitting diodes could be beneficially used in next generation retinal imaging systems.
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