Apple Preload Halved the Postprandial Glycaemic Response of Rice Meal on in Healthy Subjects.

Jiacan Lu,Yixue Wu,Linlin Wang,Zhihong Fan,Ying Zhou,Ruixin Zhu,Wenqi Zhao

doi:10.3390/nu11122912

Abstract

This study aimed to investigate the possible glycemic effect of apple preload on acute postprandial glycemic responses (GRs) of a following rice meal, comparing with its co-ingestion counterpart and an apple sugar solution preload, based on equal carbohydrates intake. In a randomized crossover trial, 18 healthy female subjects consumed (1) rice, (2) co-ingestion of apple and rice (A+R), (3) apple preload and rice (PA+R), and (4) rice with sugar solution preload (same sugar profile as in apple) (PSS+R). Acute postprandial GR tests and subjective satiety tests were carried out for each test food. Compared with rice reference, the PA+R achieved a 50% reduction of the iAUC0-120, a 51.4% reduction of the average peak value, and a 52.6% reduction of glycemic excursion in 240 min, while the PSS+R showed 29.7% and 31.6% reduction of peak value and glycemic excursion, respectively. No significant differences were found between R and PA+R in any of the satiety characteristics. Compared with rice control, apple preload of 15 g available carbohydrates remarkably lowered the acute postprandial GR without negative effect on satiety. The sugar component may partly contribute to the glycemic suppressing effect of the apple preload.

Highlights

Blood glucose management plays a role in the prevention of diabetes, cardiovascular diseases, obesity, certain cancers, and other diseases such as acne [1,2,3,4]
Among the postprandial glycemic management strategies, increasing attention has been on preload, as mounting evidence indicates that a small load of macro-nutrients ingested at a fixed interval before a meal can result in a milder postprandial glycemic and insulin response, higher postprandial satiety, and lower glycated hemoglobin (HbA1c), inflammatory markers, and serum lipids levels [5,6,7,8]
The present study has shown that adding apple to white rice meals, on the basis of equal carbohydrates intake, could suppress the acute postprandial glycemic responses (GRs), and this effect was more pronounced when the apple was given as preload

Summary

Introduction

Blood glucose management plays a role in the prevention of diabetes, cardiovascular diseases, obesity, certain cancers, and other diseases such as acne [1,2,3,4]. Fruit consumption is encouraged by health professionals as it is conducive to the prevention of cardiovascular diseases by providing antioxidants, potassium, and dietary fiber [17,18]. A number of studies indicate that the substitution of high glycemic index (GI) refined rice with certain fruits or dried fruits can improve postprandial GR [19,20], insulin responses [20], and HbA1c levels [21]

Objectives

Methods

Conclusion