Abstract
On the 6th day after a single intraperitoneal injection of cyclophosphamide in a dose of 200 mg/kg body weight into mice of lines DBA/2, C57BL/6j, and F1(C57BL/6j×CBA) foci of hematopoiesis appeared in the liver and lymph glands. This process was accompanied by the appearance of hematopoietic stem cells in the liver. Their number reached a maximum on the 6th and 9th days. On the 12th day their number fell, but it was still higher than in animals receiving an injection of a suspension of normal liver cells. After exhaustion of the pool of bone marrow and spleen stem cells by myleran, a subsequent injection of cyclophosphamide did not induce the appearance of foci of hematopoiesis and stem cells in the liver.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
