Abstract
Apparent molar enthalpies have been determined as a function of concentration by heat conduction calorimetry for aqueous solutions of the amphiphilic drugs chlorpromazine hydrochloride, promethazine hydrochloride, promazine hydrochloride, and imipramine hydrochloride. The concentration dependence of the apparent molar entalpy could be quantitatively described using a mass-action model of association based on the Guggenheim equations for the activity coefficients of mixed electrolytes
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