Abstract
An apparatus has been designed to estimate the respiratory tract distribution of therapeutic aerosols. It consists of an accurate life size model of the human oral passage extending from lips to mid-trachea, a Y branch for flow adjustment and a cascade impactor. Aerosol delivery devices are positioned to introduce the generated aerosol into the oral entrance, simulating their in vivo delivery. The aerosol which penetrates the oral airway model cast passes to the cascade impactor for aerodynamic size classification to estimate regional delivery to the bronchial and pulmonary zones. The apparatus has been tested using a metered dose inhaler (MDI) at a range of inspiratory flow rates.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
